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May 1984

Myasthenic Syndrome and Small Cell Cancer of the Lung: Variable Response to Antineoplastic Therapy

Author Affiliations

From the Department of Internal Medicine, University of Iowa College of Medicine, Iowa City (Dr Clamon), and the Department of Medicine, University of Toronto and Toronto General Hospital (Drs Evans, Shepherd, and Humphrey).

Arch Intern Med. 1984;144(5):999-1000. doi:10.1001/archinte.1984.00350170157026

• Myasthenic syndrome secondary to small cell lung cancer has been studied In five patients who achieved complete remission with chemotherapy. The relationship between response or relapse of the neoplasm to therapy and the activity of the myasthenic syndrome is variable. This inconsistent clinical correlation between the cancer and its paraneoplastic syndrome is examined in view of current data on the immunologic basis of myasthenic syndrome.

(Arch Intern Med 1984;144:999-1000)