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June 1984

RBC Fragmentation and Thymoma

Author Affiliations

From the Division of Hematology (Drs Rauch, Tartaglia, and Kaufman) and the Department of Surgery (Dr Kausel), St Peter's Hospital, Albany (NY) Medical College. Dr Kaufman is now with the Department of Medicine, Chicago Medical School.

Arch Intern Med. 1984;144(6):1280-1282. doi:10.1001/archinte.1984.00350180228032

• Thrombocytopenia and hemolytic anemia with fragmented RBCs were discovered in a 70-year-old woman with a large mediastinal mass. Investigation of the cause of the hematologic findings was negative. The mass was surgically excised and proved to be a thymoma of spindle cell type. The hemogram findings returned to normal within a month of surgery. We postulate the thymoma as the source of the RBC fragmentation and thrombocytopenia and explore the relationship between tumors and the hematologic findings.

(Arch Intern Med 1984;144:1280-1282)

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