• Thrombocytopenia and hemolytic anemia with fragmented RBCs were discovered in a 70-year-old woman with a large mediastinal mass. Investigation of the cause of the hematologic findings was negative. The mass was surgically excised and proved to be a thymoma of spindle cell type. The hemogram findings returned to normal within a month of surgery. We postulate the thymoma as the source of the RBC fragmentation and thrombocytopenia and explore the relationship between tumors and the hematologic findings.
(Arch Intern Med 1984;144:1280-1282)
Rauch AE, Tartaglia AP, Kaufman B, Kausel H. RBC Fragmentation and Thymoma. Arch Intern Med. 1984;144(6):1280–1282. doi:10.1001/archinte.1984.00350180228032
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