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June 1984

Methylprednisolone in Status Asthmaticus

Author Affiliations

New Haven, Conn

Arch Intern Med. 1984;144(6):1305. doi:10.1001/archinte.1984.00350180255040

To the Editor.  —I would like to comment on the recent study by Haskell et al1 in the July Archives.First, this article was welcomed, since there is a paucity of well-designed and executed studies using corticosteroids for treating status asthmaticus. Second, I would disagree slightly with the authors' interpretation of their data. I think it is unfair to say that the lowest steroid dose was ineffective. Although the forced expiratory volume in 1 s (FEV1) of the low-dose group did not improve statistically compared with the baseline FE V1, this seems to be a result of the large standard error and the fact that there were three nonresponders in the group. From the information in their Figure, one would guess that the FEV1 of the low-dose group was not statistically different from the other two groups after three days.I would generally agree with the

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