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September 1984

Pneumococcal Vaccine Strategy: Feasibility of a Vaccination Program Directed at Hospitalized and Ambulatory Patients

Author Affiliations

From the Infectious Diseases Unit, Department of Medicine, St Mary's Hospital, Rochester, NY (Dr Magnussen); the Infectious Diseases (Dr Valenti) and General Medicine Units (Dr Mushlin), Department of Medicine, Strong Memorial Hospital, University of Rochester (NY) School of Medicine and Dentistry.

Arch Intern Med. 1984;144(9):1755-1757. doi:10.1001/archinte.1984.00350210067010

• A prospective analysis of patients hospitalized with pneumococcal infection at two Rochester (NY) hospitals was performed during an 18-month period to assess the feasibility of a pneumococcal vaccination program directed at inpatients. Of the 113 patients hospitalized with pneumococcal infection, only nine patients (8%) had previously received pneumococcal vaccine and 76 patients (67%) had been hospitalized at least once In the previous three years. Of the 104 patients who had a source of regular medical care, 100% had made at least one outpatient visit In the previous three years. The association between the acquisition of a serious pneumococcal infection and hospitalization within the previous three years suggests that a vaccination strategy directed at hospitalized high-risk patients would be potentially effective. Also, vaccination of high-risk ambulatory patients remains a viable strategy to prevent serious pneumococcal infection.

(Arch Intern Med 1984;144:1755-1757)