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September 1984

Unilateral Adrenal Hypertrophy in Ectopic ACTH Syndrome

Author Affiliations

From University of Maryland Cancer Center, University of Maryland Hospital, Baltimore (Dr Sigman), and the Division of Endocrinology, Hahnemann Medical College, Crozer-Chester Medical Center, Chester, Pa (Dr Wallach).

Arch Intern Med. 1984;144(9):1869-1870. doi:10.1001/archinte.1984.00350210199036

• Ectopic adrenocorticotropic hormone (ACTH) syndrome was the first ectopic hormone syndrome to be described. It has been shown that most lung tumors have elevated ACTH levels, and most patients with these tumors have high serum ACTH values. The few cases in which Cushing's syndrome develops are presumed to have bilateral adrenal hyperplasia. We encountered a case of ectopic ACTH-caused Cushing's syndrome due to unilateral adrenal hypertrophy.

(Arch Intern Med 1984;144:1869-1870)