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October 1984

Cellular Biology of the Renin-Angiotensin Systems

Author Affiliations

From the Section on Hypertensive Diseases, Department of Internal Medicine, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans.

Arch Intern Med. 1984;144(10):2037-2041. doi:10.1001/archinte.1984.04400010159025

• The renin-angiotensin system is a major determinant of arterial pressure and intravascular volume in human beings. Recent evidence, however, suggests that renin can be synthesized at local tissue sites and that these local renin-angiotensin systems subserve important physiologic functions. in addition, It appears that there exist Intracellular renin-angiotensin "systems" capable of generating angiotensin II intracellularly.

(Arch Intern Med 1984;144:2037-2041)

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