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October 1984

Angioimmunoblastic Lymphadenopathy With ParaproteinemiaAnalysis of the Clinical and Biological Characteristics and Their Prognostic Significance

Author Affiliations

From the Department of Medicine, Hôpital de St Gilles (Drs Soupart, de Saint-Georges, Salhadin, Sztern, and Lustman); and the Department of Immunology, Hôpital Erasme, Free University (Dr Wybran), Brussels.

Arch Intern Med. 1984;144(10):2092-2093. doi:10.1001/archinte.1984.04400010219041

• We report a case of a double M component appearing in the course of angioimmunoblastic lymphadenopathy with dysproteinemia (AILD). Lymphocyte function, especially the decrease in T-suppressor cells, could play an essential role in the mechanisms of the disease. In the presence of an M component, the prognosis for AILD seems to be more pessimistic. Arguments for considering AILD as a premalignant disease are reviewed.

(Arch Intern Med 1984;144:2092-2093)