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—As Dr Saleh observes, there is a growing body of evidence that shows that nonpersimmon phytobezoar formation is commonly associated with altered gastric motility. However, it has not been proven whether this is a causal association. If nonpersimmon phytobezoar formation occurs as a result of abnormal gastric motility, then metoclopramide would be expected to decrease the rate of phytobezoar formation and recurrence.
In our study, we attempted to define the clinical picture of patients with a nonpersimmon phytobezoar and report the success rate for the various efforts that were used to nonsurgically ablate the concretions. Metoclopramide was not used in a sufficient number of our patients to permit us to confirm Dr Saleh's observations. However, we fully support Dr Saleh's suggestion that metoclopramide be studied in a double-blind, prospective effort to ascertain its effects on preventing nonpersimmon phytobezoar recurrence.
Zarling EJ, Thompson L. Nonpersimmon Gastric Phytobezoars-Reply. Arch Intern Med. 1985;145(3):577–578. doi:10.1001/archinte.1985.00360030229055
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