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April 1985

Nortriptyline-Induced Severe Hyperventilation

Author Affiliations

From the Department of Internal Medicine, University of Missouri-Columbia, and the Harry S Truman Memorial Hospital, Columbia, Mo.

Arch Intern Med. 1985;145(4):746-747. doi:10.1001/archinte.1985.00360040184041

• A 61-year-old man with end-stage renal disease developed severe hyperventilation following nortriptyline hydrochloride usage for depression. He required mechanical ventilation and paralysis to correct severe respiratory alkalosis. To our knowledge, nortriptyline usage has not been previously associated with hyperventilation.

(Arch Intern Med 1985;145:746-747)