• To our knowledge, the association of the plasmacytoid variety of small-cell lymphoma with primary Sjögren's syndrome has not been reported. We describe a patient with SS who developed plasmacytoid small-cell lymphoma. As opposed to the commonly detected IgM, the lymphocyte surface immunoglobulins contained monoclonal IgA/κ light chains. In addition to the unique immunopathologic features, the impressive response to chemotherapy and the importance of surface immunoglobulin markers in the diagnosis of malignancy in Sjögren's syndrome are discussed.
(Arch Intern Med 1985;145:935-937)
Askari AD, Laqui CC, Rassiga AL, Hogrefe WR, Laipply TC. Small-Cell Lymphoma and Sjögren's Syndrome: Lymphoplasmacytic Subvariant of Small-Cell Lymphoma With IgA/? Immunoglobulin Surface Markers. Arch Intern Med. 1985;145(5):935–937. doi:10.1001/archinte.1985.00360050205039
Best of JAMA Network 2022
Customize your JAMA Network experience by selecting one or more topics from the list below.