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Article
February 1986

Metabolic Acidosis: Development in Two Patients Receiving a Potassium-Sparing Diuretic and Total Parenteral Nutrition

Author Affiliations

From the Section of Gastroenterology, Department of Medicine and the Nutrition Support Service, University of Chicago.

Arch Intern Med. 1986;146(2):343-345. doi:10.1001/archinte.1986.00360140173025
Abstract

• Two patients developed a metabolic acidosis associated with a normal undetermined anion concentration while receiving a potassium-sparing diuretic and total parenteral nutrition. In both cases the metabolic acidosis resolved within one week after discontinuing administration of the diuretic. The use of potassium-sparing diuretics in a patient receiving total parenteral nutrition requires caution and continued monitoring for this potential drug-nutrient interaction.

(Arch Intern Med 1986;146:343-345)

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