Antithrombotic therapy has been recommended at one time or another for nearly every A cardiovascular disorder that is seen in daily practice.In determining which patients should be treated, the clinician faces a most difficult task because the information for the efficacy of antithrombotic therapy for many disorders is incomplete and the recommendation to use antithrombotic therapy has been based on case series or clinical judgment. In recent years, a number of randomized studies have been performed, which have provided definitive information on the value of antithrombotic therapy in a number of cardiovascular disorders including: the prevention and treatment of venous thromboembolism; treatment of unstable angina; prevention of shunt thrombosis after aortocoronary bypass surgery, and treatment of transient cerebral ischemia. However, information is incomplete for many common disorders and there are few important areas of medicine in which the lack of consensus on appropriate management is so evident.To
Dalen JE, Hirsh J. American College of Chest Physicians and the National Heart, Lung, and Blood Institute National Conference on Antithrombotic Therapy. Arch Intern Med. 1986;146(3):462–472. doi:10.1001/archinte.1986.00360150060007
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