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June 1986

Staphylococcus aureus Endocarditis: A Review of 119 Cases

Author Affiliations

From the Department of Clinical Microbiology at Hvidovre Hospital (Dr Espersen) and the Department of Antibiotics (Dr Frimodt-Møller), Statens Seruminstitut, Copenhagen.

Arch Intern Med. 1986;146(6):1118-1121. doi:10.1001/archinte.1986.00360180110018

Staphylococcus aureus endocarditis cases in Denmark from 1976 to 1981 were reviewed. A total of 119 patients—61 female and 58 male, with a median age of 63 years (range, 1 month to 85 years)—fulfilled the diagnostic criteria. Community-acquired infections were most common (62%), but the frequency of hospital-acquired cases (38%) was greater than in earlier reports. The clinical picture was relatively nonspecific, and 32% of the patients had no heart murmurs initially. In 65 cases (55%), endocarditis was not suspected clinically, and the diagnosis was first obtained at autopsy. The mortality was 71% and correlated with age, hospital-acquired infection, and the presence of heart failure and arterial embolism.

(Arch Intern Med 1986;146:1118-1121)

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