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June 1986

Continuous Ambulatory Peritoneal Dialysis for Psoriasis: A Report of Four Cases

Author Affiliations

From the Departments of Medicine (Drs Twardowski, Nolph, and Khanna, and Mss Prowant and Schmidt) and Dermatology (Dr Anderson), University of Missouri-Columbia; the Departments of Medicine (Drs Lempert and Whittier) and Dermatology (Dr Welton), West Virginia University, Morgantown; and the Department of Nephrology/Hypertension, Central Plains Clinic, Sioux Falls, SD (Dr Lankhorst).

Arch Intern Med. 1986;146(6):1177-1179. doi:10.1001/archinte.1986.00360180191028

• Four patients with psoriasis were treated with continuous ambulatory peritoneal dialysis (CAPD). Two were being treated for renal failure; the other two had normal renal function and were being treated exclusively for psoriasis. With CAPD at a rate of three to four exchanges per day, the psoriasis cleared completely in the two patients with renal failure and improved in the other two. In the patients without renal failure, low-flow peritoneal dialysis (one exchange per day) seemed to be of some value in maintaining remission but was ineffective in treating more active disease. Long-term therapy (≥12 weeks) with three or four daily exchanges may be needed for initial complete remission, and continuous treatment may be needed to prevent relapse. Thus, CAPD shows promise for the study of psoriasis and may be a last-resort treatment for severe, disabling cases.

(Arch Intern Med 1986;146:1177-1179)

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