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July 1986

Mitral Valve Prolapse in Psoriatic Arthritis

Author Affiliations

From the Departments of Medicine (Drs Pines, Ehrenfeld, Kaplinsky, and Samra) and Dermatology (Dr Ronnen) and the Cardiac Rehabilitation Institute (Drs Fisman and Kellermann), Chaim Sheba Medical Center, Tel Hashomer, and Sackler School of Medicine, Tel Aviv University, Israel.

Arch Intern Med. 1986;146(7):1371-1373. doi:10.1001/archinte.1986.00360190149021

• Twenty-five patients with psoriatic arthritis were studied by echocardiography in view of the known association of related seronegative arthropathies with aortic-valve lesions. The study group included 15 men and ten women with a mean age of 46.5 ±14.6 years. Twenty-two patients suffered from peripheral disease whereas three also had axial involvement. No aortic-valve lesions were found; however, mitral-valve prolapse (MVP) was detected in 14 patients (56%), nine men and five women. The mean age, mean duration of psoriasis, and mean duration of arthritis were similar in patients with and without MVP. HLA tissue typing, which was done in nine patients with MVP, revealed only one patient with HLA-B27. There was no predominance of any of the typical antigens found in psoriasis (HLA-B13, HLA-Cw6). In a control group of 32 psoriatic patients without arthritis, only two (6.4%) suffered from MVP.

(Arch Intern Med 1986;146:1371-1373)

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