We are pleased to learn that our colleagues in Japan have had salutary results from using a tetracyclinelike agent for sclerosing a thyroid cyst. We think their suggestion for using a polytef (Teflon) catheter rather than a needle for injection of the sclerosing agent to avoid extravasation is a perfectly reasonable one, and intend to try it ourselves. Although we assume the pain experienced by two of our patients was due to extravasation of the sclerosing agent, we are not certain of this, and would continue to advise addition of a small amount of a local anesthetic agent to the sclerosing solution as we have previously described.1
Ryan WG. Sclerosing Thyroid Cysts Using a Polytef Intravenous Cannula-Reply. Arch Intern Med. 1986;146(10):2088. doi:10.1001/archinte.1986.00360220270052
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