Newer blood culture techniques, such as lysis-centrifugation and lysis-filtration, increase the sensitivity of methods for detecting microorganisms in the blood by permitting rapid removal of the microbes from microbicidal serum factors and antibiotics. These techniques also maximize cultural conditions for isolate recovery. A lysis-centrifugation (LC) blood culture tube has been developed, and represents a practical blood culture system which improves recovery. However, contamination of cultures with the LC system is significantly greater than with conventional broth systems.1 According to the study reported in the present issue of the Archives by Walker et al,2 the cost at the Mayo Clinic of technician time and materials is equivalent to the cost of a conventional blood culture system with routine subcultures.
Walker et al focus on the clinical impact of enhanced detection of Staphylococcus aureus by the LC blood culture system compared with a conventional broth system. The bottom line is that the
Sheagren JN. Staphylococcus aureus Bacteremia: Potential Impact of a New Blood Culture Technique. Arch Intern Med. 1986;146(12):2323–2324. doi:10.1001/archinte.1986.00360240037005
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