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December 1986

Paget's Disease of Bone in Patients With Gout

Author Affiliations

From the Rheumatology Section, Department of Medicine, Medical College of Pennsylvania, Philadelphia (Dr Lluberas-Acosta); the Departments of Radiology (Dr Hansell) and Medicine (Dr Schumacher), University of Pennsylvania School of Medicine, Philadelphia; and the Veterans Administration Medical Center, Philadelphia (Drs Lluberas-Acosta, Hansell, and Schumacher).

Arch Intern Med. 1986;146(12):2389-2392. doi:10.1001/archinte.1986.00360240121021

• In a study designed to evaluate the radionuclide images in patients with gout, six (23%) of the 26 patients had clear evidence of Paget's disease of bone by technetium Tc 99m medronate imaging. A reference population consisting of 333 technetium Tc 99m medronate bone scans ordered for other reasons was reviewed, and only seven scans (2.1%) were found to have evidence of Paget's disease. This difference was found to be highly significant. All cases of Paget's disease were confirmed by independent radiologic evaluation. We conclude that there is a significant association between Paget's disease and gout, the basis for which is not yet known.

(Arch Intern Med 1986;146:2389-2392)

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