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February 1987

Mesothelioma as Carcinoma?

Arch Intern Med. 1987;147(2):207. doi:10.1001/archinte.1987.00370020027018

To the Editor.  —I greatly enjoyed the article by Schroeter et al1 in the September 1986 issue of the Archives that reported a case of malignant pleural mesothelioma associated with the nephrotic syndrome and in which the renal histology was consistent with minimal-change glomerular disease. The authors point out in their article that when carcinomas are the cause of the nephrotic syndrome, the renal histology is usually consistent with membranous disease. First, the authors report that only ten cases of minimalchange glomerular disease have been reported in association with carcinomas, then they report an 11th case, a case of minimal-change glomerular disease associated with malignant mesothelioma. They also say that lymphoproliferative diseases, on the other hand, cause minimal-change glomerular disease when they cause the nephrotic syndrome. Though their report is quite significant, I wish to take exception with their referring to mesothelioma as carcinoma. Technically, mesothelioma is a sarcoma.

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