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Article
April 1987

ß-Adrenergic Blocking Agents in the Treatment of Hypertension: Choices Based on Pharmacological Properties and Patient Characteristics

Arch Intern Med. 1987;147(4):654-659. doi:10.1001/archinte.1987.00370040036007
Abstract

• Drugs that block β-adrenergic receptors have become one of the most widely used classes of drugs to treat hypertension. This review puts the use of β-blockers as monotherapy for hypertension in perspective and provides reasons for choosing among the several β-blockers available. The major reasons for discriminating within this class of drugs are related to differences in concomitant clinical conditions, differences in patient responses, and intrinsic differences among the β-blockers. These differences relate to special properties such as β-agonist activity (intrinsic sympathomimetic activity), β1-selectivity, and concomitant α-blockade, as well as differences in side effect profiles, excretion characteristics, and length of action of the various drugs.

(Arch Intern Med 1987;147:654-659)

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