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May 1987

Streptococcus mitis: A Cause of Serious Infection in Adults

Author Affiliations

From the Departments of Medicine (Dr Catto) and Microbiology (Dr Jacobs), Case Western Reserve University School of Medicine, University Hospitals, and the Cleveland Veterans Administration Medical Center (Dr Shlaes), Cleveland.

Arch Intern Med. 1987;147(5):885-888. doi:10.1001/archinte.1987.00370050081014

• Twenty strains of Streptococcus mitis were isolated from blood or body fluids at the Cleveland Veterans Administration Medical Center from Jan 1,1981, to April 30,1984. Fifteen (75%) isolates were considered contaminants. Five (25%) were clinically important and associated with a serious infection of the oropharynx or gastrointestinal tract (three of five), endovascular system (one of five), or a prosthetic hip. Four of five patients required surgical intervention for treatment. Two of five died; one death was directly attributable to S mitis infection. Eighteen strains were available for detailed bacteriologic study. Three strains had a minimum inhibitory concentration of greater than 0.1 μg/mL of penicillin and six other strains were tolerant to penicillin. This review suggests that S mitis can be an important pathogen in adults and may cause infections other than endocarditis.

(Arch Intern Med 1987;147:885-888)