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May 1987

Quantitation of Proteinuria by the Use of Protein-to-Creatinine Ratios in Single Urine Samples

Arch Intern Med. 1987;147(5):943-944. doi:10.1001/archinte.1987.00370050135022

• Measurements of protein-to-creatinine ratios in single-voided urine samples were compared with 24-hour urinary protein excretions for quantitation of proteinuria in inpatients and outpatients. Patients included those representing a broad spectrum of renal diseases, a wide range of proteinuria, and various degrees of reduction in glomerular filtration rate. Protein-to-creatinine ratios in single-voided urine samples correlated well with measurements of 24-hour urinary protein. This simple single-voided test is reliable and useful in the screening, assessment, and follow-up of proteinuria and avoids the problems associated with 24-hour urine collection.

(Arch Intern Med 1987;147:943-944)