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June 1988

'Toxic Strep Syndrome': A Manifestation of Group A Streptococcal Infection

Author Affiliations

From the Divisions of Pulmonary and Critical Care Medicine (Drs Bartter and Curley) and Infectious Diseases (Drs Dascal and Carroll), University of Massachusetts Medical School, Worcester. Dr Dascal is now with the Department of Medicine, McGill University, Montreal.

Arch Intern Med. 1988;148(6):1421-1424. doi:10.1001/archinte.1988.00380060185032

• Three patients presented with multisystem disease that shared many of the features of toxic shock syndrome. Bacteriologic and serologic evidence strongly suggested that group A β-hemolytic Streptococcus had caused the illnesses. Group A streptococcal infection may be an underdiagnosed cause of a toxic streptococcal syndrome, a syndrome of multisystem disease apparently mediated by toxins.

(Arch Intern Med 1988;148:1421-1424)