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July 1988

Gluten-Sensitive Enteropathy and Systemic Lupus Erythematosus

Author Affiliations

From the Division of Gastroenterology, Department of Medicine, Beth Israel Hospital and Harvard Medical School, Boston. Dr Rustgi is now with the Gastrointestinal Unit, Massachusetts General Hospital, Boston.

Arch Intern Med. 1988;148(7):1583-1584. doi:10.1001/archinte.1988.00380070079019

• A patient with systemic lupus erythematosus developed gluten-sensitive enteropathy, or celiac sprue. The patient's histocompatibility antigens included HLA-B8 and HLA-DR3, previously found to have a high frequency in gluten-sensitive enteropathy and possibly increased as well in systemic lupus erythematosus. Such histocompatibility antigens are common to a variety of autoimmune disorders. An immune basis for the association is discussed herein.

(Arch Intern Med 1988;148:1583-1584)

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