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September 1988

Wegener's Granulomatosis Treated With Sulfamethoxazole-Trimethoprim: Report of a Case

Arch Intern Med. 1988;148(9):2065-2066. doi:10.1001/archinte.1988.00380090125028

• Wegener's granulomatosis has traditionally been treated with steroids and cyclophosphamide. However, sulfamethoxazole-trimethoprim has been shown to be effective. We used it to treat a patient with this disease who had pulmonary Infiltrates, sinusitis, and evidence of renal disease manifested by hematuria and red cell casts. After two months of therapy with sulfamethoxazole-trimethoprim, his hematologic and radiologic values returned to normal.

(Arch Intern Med 1988;148:2065-2066)