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October 1988

Chlamydia Trachomatis Pneumonia in a Patient With Multiple Myeloma

Arch Intern Med. 1988;148(10):2302-2303. doi:10.1001/archinte.1988.00380100138035

To the Editor.  Chlamydia trachomatis pneumonia is common in the newborn. It is, however, a rare event in adults, even in the immunocompromised host. In most of the reported cases the diagnosis had been made serologically. In addition to the few culture-proven cases the following patient is described.14

Report of a Case.  —In 1974 multiple myeloma (IgG κ) was diagnosed in a 39-year-old woman, initially treated with melphalan and prednisone, and subsequently with courses of cyclophosphamide, vincristine, and prednisone. Because of recurrent infections, mainly due to Escherichia coli, a prophylactic therapy of norfloxacin (400 mg, twice a day) was given.In January 1987, she was admitted because of a temperature of up to 39.6°C of two weeks duration. Ten days before admission she had noticed an infiltrate on the right thigh and she had a nonproductive cough for one week. A few fine rales were heard over the