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March 1989

Catheter-Related Fungemia by Hansenula anomala

Arch Intern Med. 1989;149(3):709-713. doi:10.1001/archinte.1989.00390030151034

To the Editor.—We read with great interest the timely report of two cases of fungemia and the review of the literature on infections by Hansenula anomala by Klein et al.1 Fifteen cases of isolation of this yeast from blood have been reported, four of which are claimed to be catheter related. However, none of these fulfill the currently accepted criteria for catheter-related septicemia based on the presence of a significant quantitative and semiquantitative culture of the catheter tip.2,3 We have recently had an occasion to attend a patient with H anomala fungemia whose origin in the Hickman catheter was well documented.

Report of a Case.—A 51-year-old woman with acute promyelocytic leukemia (M3) in complete remission was admitted to the hospital with a five-day history of high fever. A Hickman catheter-related sepsis caused by Staphylococcus epidermidis was detected, and she received a 15-day course of vancomycin intravenously

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