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April 1989

Delayed Neurologic Display in Murine Typhus: Report of Two Cases

Author Affiliations

From the Rusinow Department of Internal Medicine C, Chaim Sheba Medical Center, Tel-Hashomer, Israel (Drs Samra, Shaked, and Maier); and the Sackler School of Medicine, Tel Aviv (Israel) University (Drs Samra and Shaked).

Arch Intern Med. 1989;149(4):949-951. doi:10.1001/archinte.1989.00390040143033

• Two cases of murine typhus with prolonged neurologic manifestations appearing after the febrile stage of the illness are described. One patient had behavioral and memory disturbances for almost 18 months after defervescence, which terminated gradually without specific therapy. The second patient had smiliar manifestations over a period of weeks that rapidly resolved after tetracycline therapy. Such phenomena were not previously described In the literature, as far as we know, although similar manifestations were noted in Rocky Mountain spotted fever.

(Arch Intern Med 1989;149:949-951)