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April 1989

Breast Carcinoma Metastatic to a Meningioma: Case Report and Review of the Literature

Author Affiliations

From the Divisions of Medical Oncology (Drs Zon, Henderson, and Skarin) and Nuclear Medicine (Drs Johns and Kaplan) and the Department of Radiology (Dr Stomper), Dana-Farber Cancer Institute, the Department of Pathology, Beth Israel Hospital (Dr Connolly), the Department of Pathology, Brigham and Women's Hospital (Dr Morris), and the Department of Radiation Therapy, Joint Center for Radiation Therapy (Dr Harris), Harvard Medical School, Boston.

Arch Intern Med. 1989;149(4):959-962. doi:10.1001/archinte.1989.00390040151036

• We describe a patient who developed an Intracranial mass that consisted of a meningioma and metastatic breast cancer. A literature review revealed 12 similar cases. In epidemiologic studies, the incidence of meningioma in patients with breast cancer is higher than expected. Both tumors are more common in women, have been reported to flare during pregnancy, and express hormone receptors. In a patient with breast cancer, an intracranial mass with radiographic features suggestive, but atypical, of a meningioma should be evaluated surgically. The lesion may represent a metastasis, a meningioma, or both.

(Arch Intern Med 1989;149:959-962)

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