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June 1989

Disease Prevention: A Link Missing

Author Affiliations

Section of Cancer Prevention H. Lee Moffitt Cancer & Research Institute PO Box 280179 Tampa, FL 33682-0179

Arch Intern Med. 1989;149(6):1253-1254. doi:10.1001/archinte.1989.00390060007001

There is evidence that dietary factors play an important role in the generation of arteriosclerosis resulting in morbidity and mortality due to cardiovascular and cerebrovascular events.1 Dietary factors have been implicated in the causation of approximately one third of all cancers.2 An excessive intake of fat or calories has been linked to cancers of the breast, prostate, uterus, and colon.3-5 The risk of developing certain cancers may be reduced by eating adequate amounts of foods that confer a degree of protection. Adequate intake of fiber, in conjunction with a reduced fat intake, is thought to be important in reducing the incidence of colon cancer.6-8 Vitamin A is necessary for the normal growth and differentiation of squamous epithelia, and adequate intake of dietary vitamin A appears to protect against cancers of the lung, esophagus, and bladder.9,10

As a result of epidemiological and laboratory research, certain guidelines

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