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November 1990

Pheochromocytoma Presenting as Rhabdomyolysis and Acute Myoglobinuric Renal Failure

Arch Intern Med. 1990;150(11):2384-2385. doi:10.1001/archinte.1990.00390220118024

• We report the case of a previously healthy young woman who presented with the sudden onset of rhabdomyolysis and myoglobinuric renal failure, requiring hemodialysis for 3 weeks. Common causes of rhabdomyolysis were ruled out; as renal function returned, severe hypertension was noted and a pheochromocytoma was diagnosed. We suggest that pheochromocytoma causes rhabdomyolysis and myoglobinuria via catecholamine-mediated vasoconstriction and skeletal muscle ischemia.

(Arch Intern Med. 1990;150:2384-2385)