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April 1991

Adult Hereditary Fructose Intolerance

Author Affiliations

From the Department of Medicine, University of Minnesota, Minneapolis (Drs Burmeister and Valdivia), and Metabolic-Endocrine and Nutrition Section, Minneapolis (Minn) Veterans Affairs Medical Center (Dr Nuttall).

Arch Intern Med. 1991;151(4):773-776. doi:10.1001/archinte.1991.00400040113025

Hereditary fructose intolerance was diagnosed in a 69-year-old man on the basis of his medical history and the response to an intravenous fructose tolerance test. Three men of the same age as our patient were used as control subjects. Since the severity may vary and affected individuals self-impose fructose and sucrose restriction, they are essentially symptom free. The diagnosis can only be suspected by taking a careful dietary history. The prevalence of this condition in adults is unknown. It is rare but is likely to be more common than data in the literature would indicate.

(Arch Intern Med. 1991;151:773-776)

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