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August 1991

Angiotensin-Converting Enzyme Inhibitors (ACE) in Congestive Heart Failure-Reply

Author Affiliations

Fresno, Calif

Arch Intern Med. 1991;151(8):1670. doi:10.1001/archinte.1991.00400080149034

In Reply.—  The article by Giles et al1 was not omitted intentionally. My article2 was originally submitted in June 1989, and, although it was not published until September 1990, the process of suggested revision precluded inclusion of the study by Giles and coworkers, which was only published in May 1989. Nevertheless, the point made by Fukuyama is well taken and deserves mention. In the article by Giles et al, lisinopril was compared with captopril in a multicenter, double-blind, randomized parallel study of 189 patients with class II, III, or IV congestive heart failure who were receiving digoxin and diuretics. At baseline, the patients assigned2 lisinopril or captopril were comparable with respect to demographic characteristics, the New York Heart Association class, etiology of congestive heart failure, and exercise duration. The conclusions made by the authors indicated, and I quote, that "Treatment with either the long-acting angiotensin-converting enzyme [ACE]