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June 1992

Congenital Neutropenia: How Low?

Author Affiliations

New York City, NY

Arch Intern Med. 1992;152(6):1329. doi:10.1001/archinte.1992.00400180165029

To the Editor.——  The entity of congenital benign neutropenia is well known. In the article by Reed and Diehl,1 published in the March issue of the ARCHIVES, an attempt at quantifying the degree of this abnormality is made. The cohort for this study consisted of individuals employed by the federal government at various levels. Not mentioned in the article was consideration for the fact that employees generally undergo a pre-employment examination that may have screened out the more severe cases of leukopenia, neutropenia, and, possibly, anemia. The true extent of this variation may be greater than implied by this article.

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