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August 1992

Life-style Changes and Lipid Lowering-Reply

Author Affiliations

Los Angeles, Calif

Arch Intern Med. 1992;152(8):1722-1725. doi:10.1001/archinte.1992.00400200145031

In Reply.—  I would like to thank Chapdelaine for his interest in my study.1 Some of his concerns have already been expressed in the editorial by Grundy2 that accompanied my article. I would, however, like to respond to some of the concerns.While it is true that most of the subjects of my study were from a select population (upper class, white, highly motivated), the results show that most individuals do, indeed, respond to lifestyle modification with major reductions in serum lipid levels. Of the 4587 subjects, 91% reduced their total cholesterol levels and 88% reduced their triglyceride levels. This would indicate that many individuals presently taking medication to lower lipid levels, with long-term side effects unknown, could use life style modification as recommended by the National Cholesterol Education Program.Chapdelaine states that the validity of my statistics is suspect because all parameters were not obtained from all

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