Hemopoiesis is a complex process that underlies the production of highly specialized cells. The mechanisms involved in this process include positive and negative feedback by humoral activities, pluripotent stem cell self-renewal and differentiation, and local interactions between stromal components of the hemopoietic microenvironment and various stem and progenitor cells.1
Tabbara IA. Erythropoietin: Biology and Clinical Applications. Arch Intern Med. 1993;153(3):298–304. doi:10.1001/archinte.1993.00410030014003
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: