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March 22, 1993

Is the Magnesium Content of Nuts a Factor for Coronary Heart Disease?

Author Affiliations

Jeanette M. Hosseini Bethesda, Md

Arch Intern Med. 1993;153(6):779-780. doi:10.1001/archinte.1993.00410060079014

We read with interest the recent article entitled "A Possible Protective Effect of Nut Consumption on Risk of Coronary Heart Disease"1 and the accompanying editorial2 in the July 1992 issue of the Archives. The results of the study showed a substantial protective effect of high nut consumption on fatal and nonfatal coronary heart disease events. A reduction in the incidence of nonfatal myocardial infarction for those who consumed only whole-wheat bread was also documented. The authors' explanation of the results centered around the unique fat and fiber content of nuts and the controversial role of vitamin E. We believe that magnesium may be an alternative explanation to the purported protective effect of the consumption of nuts on coronary heart disease.

A number of studies have documented an inverse relationship between magnesium intake and the risk of coronary heart disease. For example, several large population studies have shown an