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July 12, 1993

Distribution of Lipid Phenotypes in Community-Living Men With Coronary Heart Disease

Author Affiliations

Marilyn Porter Manchester, England

Arch Intern Med. 1993;153(13):1609. doi:10.1001/archinte.1993.00410130131014

Rubins et al have recently1 emphasized the importance of lipids in men with coronary heart disease. We have also been carrying out an apparently similar analysis in male survivors of myocardial infarction (proven by electrocardiographic changes and raised levels of creatine kinase), and have recruited 73 nondiabetic men with a mean age of 59 years (standard deviation [SD], 8). In these men, the routine fasting lipid profile was as follows: total cholesterol, 6.1±0.9 mmol/L (236±35 mg/dL); lowdensity lipid cholesterol (LDL-C), 4.0±0.9 mmol/L (155±35 mg/dL) (estimated on 67 men), high-density lipid cholesterol (HDL-C), 1.1±0.3 mmol/L (43±12 mg/dL); and triglycerides, 2.3±1.5 mmol/L (204±133 mg/dL). These data were controlled by lipid levels derived from an equal number of age-matched asymptomatic men attending other nonvascular hospital clinics (eg, varicose veins, endoscopy). The lipid profile of these control men was as follows: cholesterol, 5.0±1.2 mmol/L (193±46 mg/dL); LDL-C, 3.0±1.2 mmol/L (116±46 mg/dL); HDL-C, 1.4±0.3