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September 13, 1993

Renal Cell Carcinoma Presenting as Polymyalgia Rheumatica: Resolution After Nephrectomy

Author Affiliations

From the Departments of Medicine (Drs Sidhom, Basalaev, and Sigal) and Molecular Genetics and Microbiology (Dr Sigal), University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick.

Arch Intern Med. 1993;153(17):2043-2045. doi:10.1001/archinte.1993.00410170133013

Renal cell carcinoma can present as a variety of paraneoplastic, nonmetastatic conditions, including vasculitis. We describe a patient who presented with the polymyalgia rheumatica syndrome but did not respond to a trial of prednisone. An asymptomatic, nonmetastatic renal cell carcinoma was found during this patient's evaluation. Nephrectomy led to resolution of the systemic complaints. Malignancy, in this case, renal cell carcinoma, can present as polymyalgia rheumatica and resolve after surgical removal of the underlying tumor.

(Arch Intern Med. 1993;153:2043-2045)