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September 27, 1993

Pituitary Apoplexy Revisited

Arch Intern Med. 1993;153(18):2165-2168. doi:10.1001/archinte.1993.00410180125014

We have read with interest two articles on the natural history of pituitary adenomas related to apoplexy1 and spontaneous infarction.2

Vidal et al,1 reporting on 12 cases of pituitary apoplexy, state that their series is among the largest reported and that unlike previous series, it includes both medically and surgically treated patients. It is obvious that they have not considered our published experiences3 on 13 medically and surgically treated patients with classical pituitary apoplexy followed up for up to 9 years. For a rare and potentially life-threatening disorder such as pituitary apoplexy, similarities emanating from two of the largest studies on this subject from different centers are a significant feature. While striking similarities exist between the two studies, there are, however, some differences in the interpretations and comments between these studies.

In our experience, pituitary apoplexy is a rare disorder in that we encountered it in