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July 10, 1995

Vancomycin-Resistant Enterococcus faecium Sepsis Following Persistent Colonization

Author Affiliations

From the Division of Infectious Diseases, the Department of Medicine (Drs Noskin and Peterson), and the Division of Clinical Microbiology, the Department of Pathology (Drs Noskin and Peterson), Northwestern University Medical School, and the Clinical Microbiology Laboratory, Northwestern Memorial Hospital (Ms Cooper and Dr Peterson), Chicago, III.

Arch Intern Med. 1995;155(13):1445-1447. doi:10.1001/archinte.1995.00430130139015

Vancomycin-resistant enterococci have emerged as important nosocomial pathogens and represent a serious threat to patients with impaired host defenses. We describe a patient with leukemia who developed prolonged colonization with vancomycin-resistant Enterococcus faecium and ultimately died of sepsis due to this multidrug-resistant organism. This case report confirms that colonization with vancomycin-resistant enterococci may last indefinitely and that asymptomatic carriage can lead to invasive infection.

(Arch Intern Med. 1995;155:1445-1447)