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October 9, 1995

Plummer-Vinson Syndrome: A Case Report and Literature Review

Author Affiliations

From the Departments of Medicine, Albuquerque Veterans Affairs Medical Center and the University of New Mexico School of Medicine, Albuquerque (Dr Hoffman), and the University of Arizona College of Medicine, Tucson (Dr Jaffe).

Arch Intern Med. 1995;155(18):2008-2011. doi:10.1001/archinte.1995.00430180122014

The Plummer-Vinson syndrome is characterized by dysphagia, iron-deficiency anemia, and esophageal webs. The webs are best diagnosed by cineradiography. Iron repletion often improves the dysphagia, although some patients require esophageal dilatation or bougienage. The syndrome is associated with an increased incidence of postcricoid carcinoma, and surveillance endoscopy is recommended.

(Arch Intern Med. 1995;155:2008-2011)