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October 28, 1996

Rhinocerebral Mucormycosis: Cure Without Surgery?

Author Affiliations

Boston, Mass

Arch Intern Med. 1996;156(19):2262-2269. doi:10.1001/archinte.1996.00440180126017

The article on rhinocerebral mucormycosis by Strasser et al1 in the February 12, 1996, issue of the Archives was both interesting and informative. To have a case of rhinocerebral mucormycosis with intracranial involvement cured by medical therapy alone is indeed rare and fascinating. Fortunately, in this case, the diagnosis was made early enough for treatment with amphotericin B lipid complex to be effective. Lipid formulations of amphotericin B are being used more extensively in recent times. It has been documented that an early diagnosis is necessary to cure this disease.2 In this context, we would like to draw attention to a case of cerebral mucormycosis that was cured with medical treatment alone.

Gollard et al3 described an intravenous drug abuser who presented with right-sided hemiparesis, slurred speech, altered mental status, and an unsteady gait. A stereotactic biopsy specimen from a left-sided basal ganglia lesion revealed wide, nonseptated

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