In their recent article, Avins and Neuhaus1 investigate whether high triglyceride levels contribute to the risk of coronary heart disease (CHD). Their conclusion is that triglyceride measurement does not provide a more useful evaluation of risk than an assessment of the subfractions that carry serum cholesterol. In the editorial discussion by Rubins,2 she states that high and very high triglyceride levels should be treated. However, Rubins also asserts that when triglyceride levels are moderately elevated, clinicians should consider these elevations only as a marker for increased risk for CHD, not an indication for therapeutic intervention.
Whayne, Jr TF, Zielke JC. Triglyceride Level: A Predictive Risk Factor for Atherosclerosis? Arch Intern Med. 2001;161(2):295–296. doi:
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