Saint et al1 focus on using silver alloy urinary catheters to decrease the risk of urinary tract infection in catheterized patients. They felt it was better to use silver-coated catheters instead of antibiotic-coated catheters because of the fear that resistance to the antibiotics would develop. They did not look at potential complications from exposure to silver alloy of a mucus membrane such as the urethra. Argyria, the name of the condition that occurs when silver is deposited in the body, can be a local or systemic problem. When a mucous membrane is exposed, argyria tends to be systemic and can lead to problems such as nausea, constipation, and even loss of night vision.2
Cymet T. Do Silver Alloy Catheters Increase the Risk of Systemic Argyria? Arch Intern Med. 2001;161(7):1014–1015. doi:
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