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Comments, Opinions, and Brief Case Reports
May 28, 2001

Septic Shock and Thrombotic Microangiopathy Due to Mycobacterium tuberculosis in a Nonimmunocompromised Patient

Arch Intern Med. 2001;161(10):1347-1348. doi:10.1001/archinte.161.10.1347

A 69-year-old woman was admitted to our medical intensive care unit for septic shock and multiple organ failure combined with thrombotic microangiopathy. The patient was of Vietnamese and Malagasy ethnic origin without any recent travel. Her medical history consisted of recurrent episodes of autoimmune IgG–mediated hemolytic anemia with thrombocytopenia and mild acute renal failure. At this time the results of viral serologic tests (human immunodeficiency virus [HIV] and hepatitis B and C), immunological tests (antinuclear antibodies and rheumatoid factor), and an electrophoresis of plasma proteins were negative. The findings from a bone marrow aspirate were normal. No specific cause was found, and the patient spontaneously improved.