A patient from Phoenix, Ariz, recently diagnosed as having diabetes mellitus has a deep tan. He read about hemochromatosis on a Web site and is concerned that he might have the condition. His mother died of congestive heart failure and his paternal uncle had diabetes mellitus and severe arthritis. He wants to obtain testing for an HFE gene mutation. He asks, "If I have the gene, could that be the reason for my diabetes mellitus? What should I do if I am tested and I have the gene? If I do not have the gene, could I still have the disease? Should my children be tested?"
Lloyd FJ, Reyna VF, Whalen P. Accuracy and Ambiguity in Counseling Patients About Genetic Risk. Arch Intern Med. 2001;161(20):2411–2413. doi:10.1001/archinte.161.20.2411
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