The first of the two patients, A, who furnish the basis of this report is a man 29 years old, who was born in Hungary, and served as a soldier in that country. During his military service he suffered much from chilblains during the winter, but he never had an attack of hemoglobinuria until December, 1902, eight months after coming to America.
During the summer of 1902 he lived in Saginaw, Mich., where he sufi'ercd much from mosquito bites.
There is absolutely no history of any infection or illness until December, 1902, when the patient first observed the attacks of hemoglobinuria, which were invariably associated with exposure to cold. vVe had no opportunity to observe any chilblains in this patient, but he says that when his feet or hands are thoroughly chilled they become very white, then blue and finally red, swollen and feverish. The swelling lasts several hours. According
HOOVER CF, STOXE CW. PAROXYSMAL HEMOGLOBIXUIUA. ACCOUNT OF TWO CASES. Arch Intern Med (Chic). 1908;II(4):392–404. doi:10.1001/archinte.1908.00050090097004
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