In 1832 Hodgkin1 called attention to the existence of a disease characterized primarily by progressive enlargement of the lymph nodes and associated, in many instances, with enlargement of the spleen. In the light of our present knowledge it appears that several of the cases originally described by Hodgkin were examples of leukemia or of glandular syphilis or tuberculosis, but that at least two were genuine instances of the affection to which Wilks,2 in 1856, gave the name of Hodgkin's disease and for which, in recent years, a definite histology has been established. Since the appearance of Wilks's paper in England, and a communication by Bonfils in France in the same year, many contributions have been made to the literature of the subject, and undoubtedly several different lesions have been described under the title of ``Hodgkin's disease"; among them leukemia, non-caseous glandular tuberculosis, lymphosarcoma and
SYMMERS D. CERTAIN UNUSUAL LESIONS OF THE LYMPHATIC APPARATUS: INCLUDING A DESCRIPTION OF PRIMARY HODGKIN'S DISEASE OF THE SPLEEN AND A CASE OF GASTROINTESTINAL PSEUDOLEUKEMIA. Arch Intern Med (Chic). 1909;IV(3):218–237. doi:10.1001/archinte.1909.00050190027003
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