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May 1912

NEPHRITIS: An Experimental and Critical Study of Its Nature, Cause and the Principles of Its Relief.

Arch Intern Med (Chic). 1912;IX(5):637-640. doi:10.1001/archinte.1912.00060170114008

After a careful reading of Fischer's latest book, the reviewer is forced to the unwelcome conclusion that its title page should proclaim it, not an experimental and critical study, but a speculative and uncritical study. The author's previous publication on edema, while exhibiting the spirit of the special pleader, rather than the judicial and conservative student, nevertheless called attention to the rôle of the tissue colloids in the production of dropsy, and served notice that the physiochemical standpoint must not be neglected in the interpretation of pathological phenomena. Now he proclaims in effect that there is no other standpoint. Physical chemistry affords to the author the sole and sufficient explanation for all the phenomena of nephritis. In his introductory paragraph he writes:

To render our argument clear, we will at once state our general conclusion:

All the changes that characterize nephritis are due to a common cause—the abnormal production

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